Skip to main content.

Complete Health Reporting: Beware of Fishy Claims for New Treatments

Complete Health Reporting: Beware of Fishy Claims for New Treatments

Picture of William Heisel

It is rare that a drug or device really is novel or that a research finding appears out of nowhere.

Reporters naturally want to focus on newly published research or a new announcement at a conference, but by focusing on one idea, it may present a drug or device as unique when in fact it is just a minor tweak on an old approach or no advancement at all. 

Gary Schwitzer, the publisher of says, “We think it’s naïve and frankly intellectually dishonest to portray something as new when it may just really be old fish wrapped in new newspaper.”

So what sorts of questions do you ask to find out whether the fish is fresh? Schwitzer has a few of those:

“How is it new? What other research has been done in this field? What specifically makes this new idea better? How has this been shown? In how many people? Over how much time? Does the new research conflict with a solid body of evidence that said something else prior to this and how could that be?”

Writers have been asking these questions for several years about the drug Acthar sold by Questcor at more than $70,000 per treatment. David E. Williams at Health Business Blog and Lisa Emrich at Brass & Ivory: Life with MS & RA in particular have been tracking Questcor’s series of price increases and run-ins with regulators.

Russ Mitchell’s writing for the dearly departed Portfolio magazine put together a great piece in 2008 called Drug Money that provided an answer to Schwitzer’s last question: What does the evidence show?

Mitchell interviewed Eric Kossoff, a pediatric neurologist at Johns Hopkins Children’s Center, who had been concerned that children with spasms who had benefited from Acthar would suffer if they couldn’t afford the drug.

Curiously, though, he found that the price hike "was one of the best things that could have happened." Why? "Because we found something better and cheaper." Far cheaper, it turns out. "We spent a few days going through all the medical literature, looking for what works, what doesn’t."

The team turned up a study from the United Kingdom that gave infants high doses of prednisolone, a well-known, generic steroid. Prednisolone had been dismissed as relatively ineffective for infantile spasms-based research that used low doses. The high doses made all the difference: The U.K. study found efficacy rates reached 70 percent and more. Johns Hopkins began using high-dose prednisolone and found it worked in about 70 percent of cases, on par with the hospital’s experience with Acthar Gel. And the price was $15 per injection-essentially free-compared with the three-injection $69,000 treatment from Questcor.

"It was like in times of war, you get focused, and amazing things come out," Kossoff says. "We don’t use [Acthar Gel] at Hopkins anymore for infantile spasms because the oral steroids [high-dose prednisolone] work just as well."

Too few reporters follow Kossoff’s lead and look at the evidence to either prove or disprove claims of a treatment’s novelty. I’ll write about one example in my next post. If you have your own ideas, send them to me at or via Twitter @wheisel.

Image by Thomas Levinson via Flickr

Leave A Comment


Soaring out-of-pocket costs, rising premiums, and shaky insurance exchanges raise urgent questions this election season. What policies might address these problems, and how do the presidential candidates’ health plans differ? This webinar will give an overview of each candidates’ policy prescriptions and provide reporters with crucial context for covering one of the election’s most important but overlooked issues.

The 2017 California Fellowship, for California-based journalists only, will be held March 5-9, 2017 in Los Angeles. This Fellowship will focus on vulnerable populations and access to care and health care reform and innovation. We also take an in-depth look at how community conditions influence individuals' prospects for health. Each Fellow receives a $1,000 stipend to assist with the costs of reporting an ambitious Fellowship project on a California health issue, as well as six months of mentoring by a Senior Fellow. Deadline to apply is Dec. 1.  For more information, go here.


Member Activities

Barrett Newkirk has shared a fellowship project

Read it.

Bill Gordon has shared a blog post

Read it.

Elizabeth Zach has shared a essay

Read it.

Samantha Caiola has shared a blog post

Read it.

Chinyere Amobi has shared a blog post

Read it.
More Member Activities

Follow Us



CHJ Icon